as in causes
the most important part of something or the reason for something
He acts as if making money is the be-all and end-all of human existence.
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Example Sentences
Recent Examples of Synonyms for be-all and end-alls
Noun
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There are multiple conditions that can lead to overactive bladder, but the National Association for Continence cites diabetes, multiple sclerosis and the nerve damage that comes with these conditions as the main causes.—
BestReviews,
Chicago Tribune,
11 Feb. 2026 -
Androw, owner of E & D Pizza in Avon and a leader on the national pizza scene is known for using pizza for good causes from hunger to fulfilling the wishes of terminally ill children.—
Pamela McLoughlin,
Hartford Courant,
11 Feb. 2026
Noun
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In a new secondary analysis of the larger trial published Monday in the Annals of Internal Medicine, Patti and her colleagues asked how different social determinants of health affected outcomes after bariatric surgery compared to medical therapy for people with type 2 diabetes and obesity.—
Elizabeth Cooney,
STAT,
19 Jan. 2026
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This research suggests that social determinants of health, including financial stress and food insecurity, may belong in the same conversation.—
Katia Hetter,
CNN Money,
16 Jan. 2026
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“Be-all and end-alls.” Merriam-Webster.com Thesaurus, Merriam-Webster, https://www.merriam-webster.com/thesaurus/be-all%20and%20end-alls. Accessed 16 Feb. 2026.
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